our
Laboratory
PNBT (Nano Biotechnology Platform) is a single-site infrastructure that uses technologies, tools and highly qualified technicians from a scientific perspective.
This laboratory deals with the development, scale up and technology transfer of nanoparticles and diagnostics systems.
It represents the main link between the research and molecular modeling associated with the identification of new lead compounds and their evolution towards products and attractive processes for pharmaceutical and cosmetic industries.
Area manager: Davide Prosperi
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Activities ___________
Tools
For the synthesis and purification:
- LNP process development (Sunshine, Unchained Labs)
- Microfluidic automated system for the formulation and scale up of nanoparticles (Dolomite)
- Microwave Synthesizers (Discover 2.0, CEM)
- Tangential flow filtration automated system (KrosFlo® Research 2i, Repligen – 5 mL-10 L)
For the characterization:
- High resolution transmission electron microscope (Jeol, JEM-2100Plus operante a 200 kv)
- Darkfield hyperspectral microscopy (Cytoviva)
- Lyophilizer (Deltek)
- Dynamic Light Scattering/Potential Z (Zetasizer Ultra Red, Malvern)
- Nanoparticle tracking analyzer (Nanosight Pro, Malvern)
- Differential Centrifugal Sedimentation (CPS disc centrifuge DC24000)
- HPLC (Infinty II 1260, Agilent)
- Benchtop NMR system (Minispec MQ20)
- FT-IR Spectofotometer (INVENIO®, Bruker)
- Bench Scanning Electron Microscope (Phenom Pro G6, ThermoFisher Scientific)
