Nano Biotechnology

NanoBio
Tecnologie



our
Laboratory


PNBT (Nano Biotechnology Platform) is a single-site infrastructure that uses technologies, tools and highly qualified technicians from a scientific perspective.

This laboratory deals with the development, scale up and technology transfer of nanoparticles and diagnostics systems.

It represents the main link between the research and molecular modeling associated with the identification of new lead compounds and their evolution towards products and attractive processes for pharmaceutical and cosmetic industries.

Area manager: Davide Prosperi

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Activities ___________

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The synthesis and characterization of organic and inorganic nanoparticles
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The study of cellular uptake and live imaging

    Tools

    For the synthesis and purification:

    • Microfluidic automated system for the formulation and scale up of nanoparticles (Dolomite)
    • Tangential flow filtration automated system (KrosFlo® Research 2i, Repligen – 5 mL-10 L)

    For the characterization:

    • High resolution transmission electron microscope (Jeol, JEM-2100Plus operante a 200 kv)
    • Darkfield hyperspectral microscopy (Cytoviva)
    • Lyophilizer
    • Dynamic Light Scattering/Potential Z (Zetasizer Nano ZS ZEN3600)
    • Nanoparticle tracking analyzer (Nanosight)
    • Differential Centrifugal Sedimentation (CPS disc centrifuge DC24000)
    • HPLC (Infinty II 1260, Agilent)

    Scientific research that makes business grow

    other ______________
    Laboratories

    Computational Molecular Design and Analysis Laboratory
    This laboratory employs computational method specifically developed to integrate experimental research.
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    Bioprospecting, development and optimization of green mining process Laboratory (PEG)
    Bioprospecting and PEG unit is designed to create innovative processes for natural extracts production to use in the cosmetic, pharmaceutical and food industry.
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    Nano-formulation and nano-cosmetology Laboratory
    This laboratory is dedicated to compounds and products formula and validation through quality control.
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    GLP ready, imaging and advanced diagnostics Laboratory
    A single group of research at the highest level in preclinical area and committed to neurological, neuro-immunological and oncological area as well.
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